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dc.contributor.authorPeacock, Oliver
dc.date.accessioned2016-10-26T09:39:01Z
dc.date.available2016-10-26T09:39:01Z
dc.date.issued2010-08
dc.identifier.citationAm J Surg. 2010 Aug;200(2):197-203. doi: 10.1016/j.amjsurg.2009.08.041. Epub 2010 Feb 1.language
dc.identifier.urihttp://hdl.handle.net/20.500.12904/1251
dc.descriptionAuthor(s) Pre or Post Print Onlylanguage
dc.description.abstractBACKGROUND: The objective of this study was to investigate whether the preoperative hematologic markers, the platelet-lymphocyte ratio (PLR), or the neutrophil-lymphocyte ratio (NLR) ratio are significant prognostic indicators in resected pancreatic ductal adenocarcinoma. METHODS: A total of 84 patients undergoing pancreatoduodenectomy for pancreatic ductal adenocarcinoma over a 10-year period were identified from a retrospectively maintained database. RESULTS: The preoperative NLR was found to be a significant prognostic marker (P = .023), whereas PLR had no significant relationship with survival (P = .642) using univariate Cox survival analysis. The median overall survival in patients with an NLR of < or =3.0 (n = 55) was 13.7, 17.0 months in those with an NLR of 3.0 to 4.0 (n = 17) and 5.9 months in patients with a value of >4.0 (n = 12) (log rank, P = .016). The NLR retained its significance on multivariate analysis (P = .039) along with resection margin status (P = .001). CONCLUSION: The preoperative NLR represents a significant independent prognostic indicator in patients with resected pancreatic ductal adenocarcinoma, whereas PLR does not.language
dc.language.isoenlanguage
dc.subjectPreoperative Markerslanguage
dc.subjectNeutrophil Lymphocyteration Prognosislanguage
dc.subjectPancreactic Cancerlanguage
dc.subjectAdenocarcinomalanguage
dc.titlePreoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio.language
dc.typeArticlelanguage


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