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dc.contributor.authorLappas, Andreas S.
dc.contributor.authorEdwards Suarez, Lori
dc.contributor.authorMorton, Sally
dc.contributor.authorSchofield, Christopher
dc.contributor.authorChristodoulou, Nikos G.
dc.date.accessioned2021-07-29T10:53:12Z
dc.date.available2021-07-29T10:53:12Z
dc.date.issued2021
dc.identifier.citationLappas, A. S., Edwards Suarez, L., Tzanetakou, V., Morton, S., Schofield, C. & Christodoulou, N. G. (2021). Factors associated with increased suicidality risk following referral for isotretinoin commencement. Australasian Psychiatry, 30(1), pp. 44-48.en_US
dc.identifier.other10.1177/10398562211029955
dc.identifier.urihttp://hdl.handle.net/20.500.12904/14778
dc.description.abstractOBJECTIVE: To establish whether there is a significant change in suicidality risk following psychiatric assessment for commencement of isotretinoin and identify factors that underpin any potential risk change. METHOD: Retrospective cohort study. Suicidality risk was defined as a combination of the following: (i) actual/intended self-harm and/or attempted/completed suicide, and (ii) increased service utilisation associated with suicidal ideation/behaviour. All patients referred to Psychiatry for assessment prior to commencement of isotretinoin between 2014 and 2019 were examined. Inclusion criteria: >16 years of age, assessed for commencement of isotretinoin, complete clinical records. Data were collected by reviewing the Electronic Patient Records. Fifty-seven patients were eligible. We employed descriptive statistics, parametric/non-parametric/normality tests and logistic regression analysis, using socio-demographic and clinical characteristics as independent parameters, and suicidality risk as the dependent parameter. RESULTS: Actual/intended self-harm/attempted suicide decreased significantly following assessment without significant change in service utilisation. Female gender, absence of protective factors and assessment by Consultation-Liaison Psychiatry were linked to increased suicidality risk, after controlling for age, ethnicity, recommendation for isotretinoin, and substance misuse. CONCLUSIONS: Psychiatric assessment is helpful before commencing isotretinoin. Female gender, and absence of ongoing psychopharmacological and/or psychological intervention and/or regular psychiatric follow-up predict increased suicidality risk among patients assessed for prescription of isotretinoin.
dc.description.urihttps://journals.sagepub.com/doi/10.1177/10398562211029955
dc.language.isoenen_US
dc.subjectSuicideen_US
dc.subjectRisk assessmenten_US
dc.subjectSelf-injurious behaviouren_US
dc.subjectDrug therapyen_US
dc.titleFactors associated with increased suicidality risk following referral for isotretinoin commencementen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.versionNAen_US
rioxxterms.typeJournal Article/Reviewen_US
refterms.panelUnspecifieden_US
refterms.dateFirstOnline2021-07-15
html.description.abstractOBJECTIVE: To establish whether there is a significant change in suicidality risk following psychiatric assessment for commencement of isotretinoin and identify factors that underpin any potential risk change. METHOD: Retrospective cohort study. Suicidality risk was defined as a combination of the following: (i) actual/intended self-harm and/or attempted/completed suicide, and (ii) increased service utilisation associated with suicidal ideation/behaviour. All patients referred to Psychiatry for assessment prior to commencement of isotretinoin between 2014 and 2019 were examined. Inclusion criteria: >16 years of age, assessed for commencement of isotretinoin, complete clinical records. Data were collected by reviewing the Electronic Patient Records. Fifty-seven patients were eligible. We employed descriptive statistics, parametric/non-parametric/normality tests and logistic regression analysis, using socio-demographic and clinical characteristics as independent parameters, and suicidality risk as the dependent parameter. RESULTS: Actual/intended self-harm/attempted suicide decreased significantly following assessment without significant change in service utilisation. Female gender, absence of protective factors and assessment by Consultation-Liaison Psychiatry were linked to increased suicidality risk, after controlling for age, ethnicity, recommendation for isotretinoin, and substance misuse. CONCLUSIONS: Psychiatric assessment is helpful before commencing isotretinoin. Female gender, and absence of ongoing psychopharmacological and/or psychological intervention and/or regular psychiatric follow-up predict increased suicidality risk among patients assessed for prescription of isotretinoin.en_US
rioxxterms.funder.project94a427429a5bcfef7dd04c33360d80cden_US


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