• Login
    View Item 
    •   Home
    • Nottinghamshire Healthcare NHS Foundation Trust
    • Conditions and Diseases
    • Mental Health and Behavioural Conditions
    • Tic Disorders
    • View Item
    •   Home
    • Nottinghamshire Healthcare NHS Foundation Trust
    • Conditions and Diseases
    • Mental Health and Behavioural Conditions
    • Tic Disorders
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of EMERCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjectsProfilesView

    My Account

    LoginRegister

    Links

    About EMERPoliciesDerbyshire Community Health Services NHS Foundation TrustLeicester Partnership TrustNHS Nottingham and Nottinghamshire CCGNottinghamshire Healthcare NHS Foundation TrustNottingham University Hospitals NHS TrustSherwood Forest Hospitals NHS Foundation TrustUniversity Hospitals of Derby and Burton NHS Foundation TrustUniversity Hospitals Of Leicester NHS TrustOther Resources

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Therapist-supported online remote behavioural intervention for tics in children and adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Author
    Hollis, Chris P.
    Hall, Charlotte L.
    Brown, Beverley J.
    Chamberlain, Liam R.
    Davies, E. Bethan
    McKenzie, Caitlin
    Khan, Kareem
    Kilgariff, Joseph
    Glazebrook, Cris
    Keyword
    Tics
    Behaviour therapy
    Tourette syndrome
    Date
    2021
    
    Metadata
    Show full item record
    DOI
    10.1016/S2215-0366(21)00235-2
    Publisher's URL
    https://www.thelancet.com/journals/lanpsy/article/PIIS2215-0366(21)00235-2/fulltext#%20
    Abstract
    Background: Exposure and Response Prevention (ERP) for tics appears a promising form of behaviour therapy for online delivery which could widen access to treatment. However, the effectiveness of ERP in general, and in particular when delivered online, remains uncertain. We evaluated the effectiveness of internet-delivered, therapist-supported and parent-assisted ERP for tics. Methods: Multi-centre, parallel group, single-blind, randomised controlled trial. Eligible participants were aged 9-17 years with Tourette syndrome/chronic tic disorder, who had not received behaviour therapy for tics within 12 months, and had a Yale Global Tic Severity Scale (YGTSS) Total Tic Severity Score (TTSS) of >15, or >10 if motor or vocal tics only. Participants were recruited via 16 patient identification centres, two study sites in England (Nottingham and London), or online self-referral, and were randomised (1:1) by blinded outcome-assessors to receive either 10 weeks of ERP or psychoeducation (active control). The primary outcome was YGTSS-TTSS at 3 months’ post-randomisation, analysis was by intention-to-treat. The mean cost per patient for the intervention were calculated. Longer term follow-ups are still on-going. Registrations are ISRCTN (ISRCTN70758207) and ClinicalTrials.gov (NCT03483493). Findings: Between 8th May 2018 and 30th September 2019, 224 participants were enrolled; 112 to ERP and 112 to psychoeducation. The sample was predominately male (177; 79%) and of white ethnicity (195; 87%). The difference between the groups on the YGTSS-TTSS was -2.29 points (95% CI: -3.86 to -0.71), a reduction favouring the ERP intervention at 3 months, an effect that increased by 6 months post-randomisation (-2.64, 95% CI: -4.56 to -0.73). The average therapist time spent supporting the intervention was 2.5 hours. The additional cost per participant of the ERP intervention compared to psychoeducation was £159 (95% CI -£53 to £370). There were two unrelated serious adverse events, both in the psychoeducation group. Interpretation: ERP is an effective behavioural therapy for tics. Digitally enabled ERP with minimal therapist contact time represents an efficient public mental health approach to improve access to behavioural therapy for tics in children and adolescents.
    Citation
    Hollis, C. P., Hall, C. L., Jones, R., Marston, L., Le Novere, M., Hunter, R., Brown, B. J., Sanderson, C., Andren, P., Bennett, S. D., et al. (2021). Therapist-supported online remote behavioural intervention for tics in children and adolescents in England (ORBIT): a multicentre, parallel group, single-blind, randomised controlled trial. The Lancet Psychiatry, 8(10), pp. 871-882.
    Type
    Article
    URI
    http://hdl.handle.net/20.500.12904/14848
    Collections
    Tic Disorders

    entitlement

     
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.