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    Current perspectives on defining and mitigating frailty in relation to critical illness

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    Author
    Banerjee, Jaydip
    Keyword
    Critical illness
    Frailty
    Geriatric rehabilitation
    ICU weakness
    Nutrition
    
    Metadata
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    DOI
    https://doi.org/10.1016/j.clnu.2021.09.017
    Publisher's URL
    https://www.clinicalnutritionjournal.com/article/S0261-5614(21)00434-9/fulltext
    Abstract
    Up to half of ICU survivors, many of whom were premorbidly well, will have residual functional and/or cognitive impairment and be vulnerable to future health problems. Frailty describes vulnerability to poor resolution of homeostasis after a stressor event but it is not clear whether the vulnerability seen after ICU correlates with clinical measures of frailty. In clinical practice, the scales most commonly used in critically ill patients are based on the assessment of severity and survival. Identification and monitoring of frailty in the ICU may be an alternative or complimentary approach, particularly if it helps explain vulnerability during the recovery and rehabilitation period. The purpose of this review is to discuss the use of tools to assess frailty status in the critically ill, and consider their importance in clinical practice. Amongst these, we consider biomarkers with potential to identify patients at greater or lesser risk of developing post-ICU vulnerability.
    Citation
    Costa, N. A., Minicucci, M. F., Pereira, A. G., de Paiva, S., Okoshi, M. P., Polegato, B. F., Zornoff, L., Villas Boas, P., Atherton, P. J., Phillips, B. E., Banerjee, J., Gordon, A. L., & Azevedo, P. S. (2021). Current perspectives on defining and mitigating frailty in relation to critical illness. Clinical nutrition (Edinburgh, Scotland), 40(11), 5430–5437.
    Type
    Article
    URI
    http://hdl.handle.net/20.500.12904/15076
    Collections
    Geriatric Medicine and Neurosciences

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