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dc.contributor.authorDhar-Munshi, Sushma
dc.date.accessioned2018-03-29T16:14:35Z
dc.date.available2018-03-29T16:14:35Z
dc.date.issued2016-03
dc.identifier.citationWilde, C, Patel, M, Lakshmanan, A, Morales, M, Dhar-Munshi, S, & Amoaku, W 2016, 'Prevalence of reticular pseudodrusen in eyes with newly presenting neovascular age-related macular degeneration', European Journal Of Ophthalmology, 26, 2, pp. 128-134.en
dc.identifier.urihttp://hdl.handle.net/20.500.12904/1509
dc.description.abstractPurpose: To use multimodal imaging to evaluate the prevalence of reticular pseudodrusen (RPD) in eyes with newly presenting neovascular age-related macular degeneration (nAMD) in a UK population and explore associations with RPD and angiographic subtypes of nAMD. Methods: A retrospective review of all spectral-domain optical coherence tomography, color fundus photographs, red-free and blue channel images, and fundus fluorescein angiograms of 202 consecutive patients who presented to a rapid access macular clinic over a 4-year period was performed. All images were graded by at least 2 ophthalmologists for the presence of RPD and choroidal neovascular membrane (CNV) subtypes. Results: A total of 231 consecutive eyes were studied, of which 131 (56.7%) were in women. Of these, 51 eyes with CNV (22.1%) had identifiable RPD, with one or more imaging methods in that eye. A total of 30.3% of patients with newly presenting CNV in either or both eyes had identifiable RPD. The RPD were bilateral in 85.4% of patients and were identified more commonly in women than men (72.5% vs 27.5%), a difference that reached statistical significance (p = 0.011). No association between RPD and any particular CNV subtype was demonstrated, including for retinal angiomatous proliferations (RAP). Conclusions: Reticular pseudodrusen have a high prevalence in eyes presenting with nAMD (22.1%), although at rates much lower than that of conventional drusen. They are largely a bilateral finding, occurring more frequently in women. Unlike other previous reports, we found no difference in their occurrence between the different subtypes of CNV including RAPs.en
dc.language.isoenen
dc.subjectOphthalmologyen
dc.subjectAge-related macular degenerationen
dc.subjectRetinal Drusenen
dc.subjectWet Macular Degenerationen
dc.subjectPrevalenceen
dc.titlePrevalence of reticular pseudodrusen in eyes with newly presenting neovascular age-related macular degeneration.en
dc.typeArticleen


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