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    Guidelines on the diagnosis and management of Waldenström macroglobulinaemia-A British Society for Haematology guideline

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    Author
    Krishna, Rajesh
    Keyword
    Waldenström macroglobulinaemia
    guideline
    Date
    2022
    
    Metadata
    Show full item record
    Publisher's URL
    https://onlinelibrary.wiley.com/doi/10.1111/bjh.18036
    Abstract
    Scope: The objective of this guideline is to provide healthcare professionals with clear guidance on the management of patients with Waldenström macroglobulinaemia. In individual patients, circumstances may dictate an alternative approach. Methodology: This guideline was compiled according to the British Society for Haematology (BSH) process at http://www.b-s-h.org.uk/guidelines/proposing-and-writing-a-new-bsh-guideline/. Recommendations are based on a review of the literature using Medline, Pubmed, Embase, Central, Web of Science searches from beginning of 2013 (since the publication of the previous guidelines) up to November 2021. The following search terms were used: Waldenström('s) macroglobulin(a)emia OR lymphoplasmacytic lymphoma, IgM(-related) neuropathy OR cold h(a)emagglutinin disease OR cold agglutinin disease OR cryoglobulin(a)emia AND (for group a only) cytogenetic OR molecular OR mutation OR MYD88 OR CXCR4, management OR treatment OR transfusion OR supportive care OR plasma exchange OR plasmapheresis OR chemotherapy OR bendamustine OR bortezomib OR ibrutinib OR fludarabine OR dexamethasone OR cyclophosphamide OR rituximab OR everolimus, bone marrow transplantation OR stem cell transplantation. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) nomenclature was used to evaluate levels of evidence and to assess the strength of recommendations. The GRADE criteria can be found at http://www.gradeworkinggroup.org. Review of the manuscript was performed by the British Society for Haematology (BSH) Guidelines Committee Haemato-Oncology Task Force, the BSH Guidelines Committee and the Haemato-Oncology sounding board of BSH. It was also on the members section of the BSH website for comment. It has also been reviewed by UK Charity WMUK; these organisations do not necessarily approve or endorse the contents.
    Citation
    Pratt, G., El-Sharkawi, D., Kothari, J., D'Sa, S., Auer, R., McCarthy, H., Krishna, R., Miles, O., Kyriakou, C., & Owen, R. (2022). Guidelines on the diagnosis and management of Waldenström macroglobulinaemia-A British Society for Haematology guideline. British journal of haematology, 10.1111/bjh.18036. Advance online publication. https://doi.org/10.1111/bjh.18036
    Type
    Other
    URI
    http://hdl.handle.net/20.500.12904/15119
    Collections
    Haematology

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