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    Phosphaturic mesenchymal tumors: radiological aspects and suggested imaging pathway

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    Author
    Hussein, Mohsin
    Rennie, Winston
    Keyword
    Fibroblast growth factor 23
    Oncogenic osteomalacia
    Phosphaturic mesenchymal tumors
    Tumor-induced osteomalacia
    Date
    2021
    
    Metadata
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    Publisher's URL
    https://link.springer.com/article/10.1007%2Fs11547-021-01412-1
    Abstract
    Phosphaturic mesenchymal tumors (PMTs) are rare mesenchymal neoplasms of soft tissue or bone origin that can give rise to a challenge in diagnostic imaging. These tumors are frequently associated with tumor-induced osteomalacia, also called oncogenic osteomalacia, which is a rare paraneoplastic syndrome characterized by ectopic secretion of fibroblast growth factor 23, a hormone that regulates serum phosphate level. PMTs show polymorphic features on both radiological findings and histological examination, causing problems in diagnosis owing to their similarity with other mesenchymal tumors. Thus, this paper aims to describe radiological aspects of PMTs and suggest an imaging pathway for accurate diagnosis throughout the evidence from the literature review.
    Citation
    Hussein, M., Cafarelli, F. P., Paparella, M. T., Rennie, W. J., & Guglielmi, G. (2021). Phosphaturic mesenchymal tumors: radiological aspects and suggested imaging pathway. La Radiologia medica, 126(12), 1609–1618. https://doi.org/10.1007/s11547-021-01412-1
    Type
    Article
    URI
    http://hdl.handle.net/20.500.12904/15123
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    Cancer
    Imaging

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