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dc.contributor.authorRichards, Caryl
dc.contributor.authorParker, Alex
dc.contributor.authorAlfuhied, Aseel
dc.contributor.authorMcCann, Gerry
dc.contributor.authorSingh, Anvesha
dc.date.accessioned2022-07-21T16:15:34Z
dc.date.available2022-07-21T16:15:34Z
dc.date.issued2022-07
dc.identifier.citationRichards, C. E., MSc, A. P., Parker, A. E., Alfuhied, A., McCann, G. P., & Singh, A. (2022). The role of 4-Dimensional flow in the assessment of bicuspid aortic valve and its valvulo-aortopathies. The British journal of radiology, 20220123. Advance online publication. https://doi.org/10.1259/bjr.20220123en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12904/15656
dc.description.abstractBicuspid aortic valve is the most common congenital cardiac malformation and the leading cause of aortopathy and aortic stenosis in younger patients. Aortic wall remodelling secondary to altered haemodynamic flow patterns, changes in peak velocity, and wall shear stress may be implicated in the development of aortopathy in the presence of bicuspid aortic valve and dysfunction. Assessment of these parameters as potential predictors of disease severity and progression is thus desirable. The anatomic and functional information acquired from 4D flow MRI can allow simultaneous visualisation and quantification of the pathological geometric and haemodynamic changes of the aorta. We review the current clinical utility of haemodynamic quantities including velocity, wall sheer stress and energy losses, as well as visual descriptors such as vorticity and helicity, and flow direction in assessing the aortic valve and associated aortopathies.
dc.description.urihttps://www.birpublications.org/doi/10.1259/bjr.20220123en_US
dc.language.isoenen_US
dc.subjectbicuspid aortic valveen_US
dc.subject4D flow MRIen_US
dc.titleThe role of 4-Dimensional flow in the assessment of bicuspid aortic valve and its valvulo-aortopathiesen_US
dc.typeArticleen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.versionNAen_US
rioxxterms.versionofrecord10.1259/bjr.20220123en_US
rioxxterms.typeJournal Article/Reviewen_US
refterms.panelUnspecifieden_US
html.description.abstractBicuspid aortic valve is the most common congenital cardiac malformation and the leading cause of aortopathy and aortic stenosis in younger patients. Aortic wall remodelling secondary to altered haemodynamic flow patterns, changes in peak velocity, and wall shear stress may be implicated in the development of aortopathy in the presence of bicuspid aortic valve and dysfunction. Assessment of these parameters as potential predictors of disease severity and progression is thus desirable. The anatomic and functional information acquired from 4D flow MRI can allow simultaneous visualisation and quantification of the pathological geometric and haemodynamic changes of the aorta. We review the current clinical utility of haemodynamic quantities including velocity, wall sheer stress and energy losses, as well as visual descriptors such as vorticity and helicity, and flow direction in assessing the aortic valve and associated aortopathies.en_US
rioxxterms.funder.project94a427429a5bcfef7dd04c33360d80cden_US


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