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dc.contributor.authorStephan, Blossom C. M.
dc.date.accessioned2022-09-09T14:49:27Z
dc.date.available2022-09-09T14:49:27Z
dc.date.issued2022
dc.identifier.citationSiervo, M., Babateen, A., Alharbi, M., Stephan, B. C. M. & Shannon, O. (2022). Dietary nitrate and brain health. Too much ado about nothing or a solution for dementia prevention? British Journal of Nutrition, 128 (6), pp.1130-1136.en_US
dc.identifier.other10.1017/S0007114522002434
dc.identifier.urihttp://hdl.handle.net/20.500.12904/15773
dc.description.abstractDementia is a significant public health priority with approximately 55 million cases worldwide, and this number is predicted to quadruple by 2050. Adherence to a healthy diet and achieving optimal nutritional status are vital strategies to improve brain health. The importance of this area of research has been consolidated into the new term ‘nutritional psychiatry’. Dietary nitrate, closely associated with the intake of fruits and vegetables, is a compound that is increased in dietary patterns such as the Mediterranean and MIND diets and has protective effects on cognition and brain health. Nitrate is characterised by a complex metabolism and is the precursor of the nitrate–nitrite–nitric oxide (NO) pathway contributing to systemic NO generation. A higher intake of dietary nitrate has been linked to protective effects on vascular outcomes including blood pressure and endothelial function. However, the current evidence supporting the protective effects of dietary nitrate on brain health is less convincing. This article aims to provide a critical appraisal of the current evidence for dietary nitrate supplementation for improving brain health and provide suggestions for future research.
dc.description.urihttps://www.cambridge.org/core/journals/british-journal-of-nutrition/article/abs/dietary-nitrate-and-brain-health-too-much-ado-about-nothing-or-a-solution-for-dementia-prevention/73673F647C780D521F7BFE9B6592D6E0en_US
dc.language.isoenen_US
dc.subjectDieteticsen_US
dc.subjectBrainen_US
dc.subjectCognitionen_US
dc.subjectDementiaen_US
dc.subjectPublic healthen_US
dc.titleDietary nitrate and brain health. Too much ado about nothing or a solution for dementia prevention?en_US
dc.typeArticleen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.versionNAen_US
rioxxterms.typeJournal Article/Reviewen_US
refterms.panelUnspecifieden_US
refterms.dateFirstOnline2022-08-16
html.description.abstractDementia is a significant public health priority with approximately 55 million cases worldwide, and this number is predicted to quadruple by 2050. Adherence to a healthy diet and achieving optimal nutritional status are vital strategies to improve brain health. The importance of this area of research has been consolidated into the new term ‘nutritional psychiatry’. Dietary nitrate, closely associated with the intake of fruits and vegetables, is a compound that is increased in dietary patterns such as the Mediterranean and MIND diets and has protective effects on cognition and brain health. Nitrate is characterised by a complex metabolism and is the precursor of the nitrate–nitrite–nitric oxide (NO) pathway contributing to systemic NO generation. A higher intake of dietary nitrate has been linked to protective effects on vascular outcomes including blood pressure and endothelial function. However, the current evidence supporting the protective effects of dietary nitrate on brain health is less convincing. This article aims to provide a critical appraisal of the current evidence for dietary nitrate supplementation for improving brain health and provide suggestions for future research.en_US
rioxxterms.funder.project94a427429a5bcfef7dd04c33360d80cden_US


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