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dc.contributor.authorPanek, Rafal
dc.date.accessioned2022-10-21T08:49:13Z
dc.date.available2022-10-21T08:49:13Z
dc.date.issued2017
dc.identifier.citationKaza, E., Dunlop, A., Panek, R., Collins, D.J., Orton, M., Symonds-Tayler, R., McQuaid, D., Scurr, E., Hansen, V. and Leach, M.O. (2017) 'Lung volume reproducibility under ABC control and self-sustained breath-holding', Journal of applied clinical medical physics, 18(2), pp. 154-162. doi: https://dx.doi.org/10.1002/acm2.12034.en_US
dc.identifier.issn1526-9914
dc.identifier.urihttp://hdl.handle.net/20.500.12904/15851
dc.description.abstractAn Active Breathing Coordinator (ABC) can be employed to induce breath-holds during CT imaging and radiotherapy of lung, breast and liver cancer, and recently during lung cancer MRI. The apparatus measures and controls respiratory volume, hence subject lung volume reproducibility is its principal measure of effectiveness. To assess ABC control quality, the intra-session reproducibility of ABC-induced lung volumes was evaluated and compared with that reached by applying the clinical standard of operator-guided self-sustained breath-holds on healthy volunteers during MRI. Inter-session reproducibility was investigated by repeating ABC-controlled breath-holds on a second visit. Additionally, lung volume agreement with ABC devices used with different imaging modalities in the same institution (MR, CT), or for a breast trial treatment, was assessed. Lung volumes were derived from three-dimensional (3D) T1-weighted MRI datasets by three observers employing semiautomatic lung delineation on a radiotherapy treatment planning system. Inter-observer variability was less than 6% of the delineated lung volumes. Lung volume agreement between the different conditions over all subjects was investigated using descriptive statistics. The ABC equipment dedicated for MR application exhibited good intra-session and inter-session lung volume reproducibility (1.8% and 3% lung volume variability on average, respectively). MR-assessed lung volumes were similar using different ABC equipment dedicated to MR, CT, or breast radiotherapy. Overall, lung volumes controlled by the same or different ABC devices agreed better than with self-controlled breath-holds, as suggested by the average ABC variation of 1.8% of the measured lung volumes (99 mL), compared to the 4.1% (226 mL) variability observed on average with self-sustained breath-holding. Copyright © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.
dc.description.urihttps://dx.doi.org/10.1002/acm2.12034en_US
dc.language.isoenen_US
dc.publisherJohn Wiley and Sons Ltden_US
dc.subjectBreast neoplasmsen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectBreath holdingen_US
dc.subjectRadiotherapyen_US
dc.titleLung volume reproducibility under ABC control and self-sustained breath-holdingen_US
dc.typeArticleen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.versionVoRen_US
rioxxterms.versionofrecord10.1002/acm2.12034en_US
rioxxterms.typeJournal Article/Reviewen_US
refterms.dateFCD2022-10-21T08:49:13Z
refterms.versionFCDVoR
refterms.dateFOA2022-10-21T08:49:13Z
refterms.panelUnspecifieden_US
refterms.dateFirstOnline2017
html.description.abstractAn Active Breathing Coordinator (ABC) can be employed to induce breath-holds during CT imaging and radiotherapy of lung, breast and liver cancer, and recently during lung cancer MRI. The apparatus measures and controls respiratory volume, hence subject lung volume reproducibility is its principal measure of effectiveness. To assess ABC control quality, the intra-session reproducibility of ABC-induced lung volumes was evaluated and compared with that reached by applying the clinical standard of operator-guided self-sustained breath-holds on healthy volunteers during MRI. Inter-session reproducibility was investigated by repeating ABC-controlled breath-holds on a second visit. Additionally, lung volume agreement with ABC devices used with different imaging modalities in the same institution (MR, CT), or for a breast trial treatment, was assessed. Lung volumes were derived from three-dimensional (3D) T1-weighted MRI datasets by three observers employing semiautomatic lung delineation on a radiotherapy treatment planning system. Inter-observer variability was less than 6% of the delineated lung volumes. Lung volume agreement between the different conditions over all subjects was investigated using descriptive statistics. The ABC equipment dedicated for MR application exhibited good intra-session and inter-session lung volume reproducibility (1.8% and 3% lung volume variability on average, respectively). MR-assessed lung volumes were similar using different ABC equipment dedicated to MR, CT, or breast radiotherapy. Overall, lung volumes controlled by the same or different ABC devices agreed better than with self-controlled breath-holds, as suggested by the average ABC variation of 1.8% of the measured lung volumes (99 mL), compared to the 4.1% (226 mL) variability observed on average with self-sustained breath-holding. Copyright © 2017 The Authors. Journal of Applied Clinical Medical Physics published by Wiley Periodicals, Inc. on behalf of American Association of Physicists in Medicine.en_US
rioxxterms.funder.project94a427429a5bcfef7dd04c33360d80cden_US


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