From the RELAY family-A story of single-branched international outcomes

Abstract

Background: Advances in surgery over the last few decades has led to the development and widespread utilization of thoracic endovascular aortic repair (TEVAR). TEVAR, due to its minimally invasive nature and potential superior outcomes, is now becoming a key focus of interest in treating pathologies of the aortic arch, which has traditionally been treated with open surgical repair. We present our findings of our international multicentre dataset documenting the efficacy of the single-branched RELAY™ endograft in terms of technical success, postoperative outcomes, and reintervention rates. Methods: Prospective data were collected and retrospectively analyzed with descriptive and distributive analysis between January 2019 and January 2022 from 17 patients treated with RELAY single-branched endoprostheses from centers across Europe. Follow-up data from 30 days and 6 months, 12 months, and 24 months postoperatively was included. Patient follow-up was evaluated in terms of postoperative outcomes, target vessel patency, and reintervention rates. Results: Technical success was achieved in all 17 patients (100%) and there were no postoperative disabling or nondisabling strokes in our single-branched RELAY cohort. The target vessel patency remained 100% during the first 30 days postoperatively; however, by the end of the follow-up period (24 months), target vessel patency was achieved in 93.7% of the patients. There were no reinterventions or deaths during the full study duration using the single-branched RELAY stent-graft. Conclusions: These results with the single-branched RELAY stent graft demonstrate favorable outcomes in comparison to the literature and demonstrate the feasibility of treatment of aortic pathology with this single-branched graft in the future. Further studies with larger patient cohorts will help us to accumulate evidence for the feasibility of the single-branched RELAY stent graft for aortic arch surgery in the future.