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dc.contributor.authorGardiner, Dale C.
dc.date.accessioned2023-05-15T14:22:20Z
dc.date.available2023-05-15T14:22:20Z
dc.date.issued2016
dc.identifier.citationDalle Ave, A.L., Gardiner, D.C. and Shaw, D.M. (2016) 'The ethics of extracorporeal membrane oxygenation in brain-dead potential organ donors', Transplant International, 29(5), pp. 612-618. doi: 10.1111/tri.12772.en_US
dc.identifier.issn1432-2277
dc.identifier.urihttp://hdl.handle.net/20.500.12904/16989
dc.descriptionFree to read online at publisher's website here: https://doi.org/10.1111/tri.12772.en_US
dc.description.abstractOrgan-preserving extracorporeal membrane oxygenation (OP-ECMO) is defined as the use of extracorporeal support for the primary purpose of preserving organs for transplantation, rather than to save the patient's life. This paper discusses the ethics of using OP-ECMO in donation after brain determination of death (DBDD) to avoid the loss of organs for transplantation. We review case reports in the literature and analyze the ethical issues raised. We conclude that there is little additional ethical concern in continuing OP-ECMO in patients already on ECMO if they become brain dead. The implementation of OP-ECMO in hemodynamically unstable brain-dead patients is ethically permissible in certain clinical situations but requires specific consent from relatives if the patient's wish to donate is not clear. If no evidence of a patient's wish to donate is available, OP-ECMO is not recommended. In countries with presumed consent legislation, failure to opt out should be considered as a positive wish to donate. If a patient is not-yet brain-dead or is undergoing testing for brain death, OP-ECMO is not recommended. Further research on OP-ECMO is needed to better understand the attitudes of professionals, families, and lay people to ensure agreement on key ethical issues. Copyright © 2016 Steunstichting ESOT.
dc.description.urihttps://doi.org/10.1111/tri.12772en_US
dc.language.isoenen_US
dc.subjectBrain deathen_US
dc.subjectOrgan donationen_US
dc.subjectBioethical issues
dc.titleThe ethics of extracorporeal membrane oxygenation in brain-dead potential organ donorsen_US
dc.typeArticleen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.versionVoRen_US
rioxxterms.versionofrecord10.1111/tri.12772en_US
rioxxterms.typeJournal Article/Reviewen_US
refterms.dateFCD2023-05-15T14:22:20Z
refterms.versionFCDVoR
refterms.panelUnspecifieden_US
html.description.abstractOrgan-preserving extracorporeal membrane oxygenation (OP-ECMO) is defined as the use of extracorporeal support for the primary purpose of preserving organs for transplantation, rather than to save the patient's life. This paper discusses the ethics of using OP-ECMO in donation after brain determination of death (DBDD) to avoid the loss of organs for transplantation. We review case reports in the literature and analyze the ethical issues raised. We conclude that there is little additional ethical concern in continuing OP-ECMO in patients already on ECMO if they become brain dead. The implementation of OP-ECMO in hemodynamically unstable brain-dead patients is ethically permissible in certain clinical situations but requires specific consent from relatives if the patient's wish to donate is not clear. If no evidence of a patient's wish to donate is available, OP-ECMO is not recommended. In countries with presumed consent legislation, failure to opt out should be considered as a positive wish to donate. If a patient is not-yet brain-dead or is undergoing testing for brain death, OP-ECMO is not recommended. Further research on OP-ECMO is needed to better understand the attitudes of professionals, families, and lay people to ensure agreement on key ethical issues. Copyright © 2016 Steunstichting ESOT.en_US
rioxxterms.funder.project94a427429a5bcfef7dd04c33360d80cden_US


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