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dc.contributor.authorCorsetti, Maura
dc.date.accessioned2024-02-07T11:56:35Z
dc.date.available2024-02-07T11:56:35Z
dc.date.issued2023
dc.identifier.citationCorsetti, M., Forestier, S. and Jimenez, M. (2023) 'Hyoscine butylbromide mode of action on bowel motility: From pharmacology to clinical practice', Neurogastroenterology & Motility, 35(4), pp. e14451. doi: 10.1111/nmo.14451 https://doi.org/10.1111/nmo.14451.en_US
dc.identifier.issn1365-2982
dc.identifier.issn1350-1925
dc.identifier.urihttp://hdl.handle.net/20.500.12904/18217
dc.description.abstractBACKGROUND: Hyoscine butylbromide (HBB) has been available for use as an antispasmodic since 1951 and is indicated for the treatment of abdominal pain associated with cramps. A previous review in 2007 summarized the evidence on the mode of action of HBB in vitro and in vivo in both animal and human studies. However, since then, novel publications have appeared within the literature and also our knowledge of what represents normal motility in humans has evolved. PURPOSE: This review is the result of the collaboration between a basic scientist and clinicians with the aim of providing an updated overview of the mechanisms of action of HBB and its clinical efficacy to guide not only use in clinical practice, but also future research. Copyright © 2022 The Authors. Neurogastroenterology & Motility published by John Wiley & Sons Ltd.
dc.description.urihttps://doi.org/10.1111/nmo.14451en_US
dc.language.isoenen_US
dc.subjectAbdominal painen_US
dc.subjectHyoscine butylbromideen_US
dc.titleHyoscine butylbromide mode of action on bowel motility: From pharmacology to clinical practiceen_US
dc.typeArticleen_US
rioxxterms.funderDefault funderen_US
rioxxterms.identifier.projectDefault projecten_US
rioxxterms.versionVoRen_US
rioxxterms.versionofrecord10.1111/nmo.14451en_US
rioxxterms.typeJournal Article/Reviewen_US
refterms.dateFCD2024-02-07T11:56:36Z
refterms.versionFCDVoR
refterms.dateFOA2024-02-07T11:56:36Z
refterms.panelUnspecifieden_US
html.description.abstractBACKGROUND: Hyoscine butylbromide (HBB) has been available for use as an antispasmodic since 1951 and is indicated for the treatment of abdominal pain associated with cramps. A previous review in 2007 summarized the evidence on the mode of action of HBB in vitro and in vivo in both animal and human studies. However, since then, novel publications have appeared within the literature and also our knowledge of what represents normal motility in humans has evolved. PURPOSE: This review is the result of the collaboration between a basic scientist and clinicians with the aim of providing an updated overview of the mechanisms of action of HBB and its clinical efficacy to guide not only use in clinical practice, but also future research. Copyright © 2022 The Authors. Neurogastroenterology & Motility published by John Wiley & Sons Ltd.en_US
rioxxterms.funder.project94a427429a5bcfef7dd04c33360d80cden_US


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