Therapeutic management of idiosyncratic drug-induced liver injury and acetaminophen hepatotoxicity in the paediatric population: A systematic review
| dc.contributor.author | Atallah, Edmond | |
| dc.contributor.author | Aithal, Guruprasad P. | |
| dc.date.accessioned | 2024-03-13T15:05:48Z | |
| dc.date.available | 2024-03-13T15:05:48Z | |
| dc.date.issued | 2022 | |
| dc.identifier.citation | Niu, H., Atallah, E., Alvarez-Alvarez, I., Medina-Caliz, I., Aithal, G.P., Arikan, C., Andrade, R.J. and Lucena, M.I. (2022) 'Therapeutic management of idiosyncratic drug-induced liver injury and acetaminophen hepatotoxicity in the paediatric population: A systematic review', Drug Safety, 45(11), pp. 1329-1348. doi: 10.1007/s40264-022-01224-w https://doi.org/10.1007/s40264-022-01224-w. | en_US |
| dc.identifier.issn | 1179-1942 | |
| dc.identifier.issn | 0114-5916 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12904/18356 | |
| dc.description.abstract | INTRODUCTION: Drug-induced liver injury (DILI) is a rare but serious adverse event that can progress to acute liver failure (ALF). The evidence for treatment of DILI in children is scarce. OBJECTIVE: We aimed to comprehensively review the available literature on the therapies for both acetaminophen overdose (APAP) and idiosyncratic DILI in the paediatric population. METHODS: We included original articles conducted in a paediatric population ( Copyright © 2022. The Author(s). | |
| dc.description.uri | https://doi.org/10.1007/s40264-022-01224-w | en_US |
| dc.language.iso | en | en_US |
| dc.subject | Systematic review | en_US |
| dc.subject | Chemical and drug induced liver injury | en_US |
| dc.subject | Acute liver failure | en_US |
| dc.subject | Paediatrics | en_US |
| dc.title | Therapeutic management of idiosyncratic drug-induced liver injury and acetaminophen hepatotoxicity in the paediatric population: A systematic review | en_US |
| dc.type | Article | en_US |
| rioxxterms.funder | Default funder | en_US |
| rioxxterms.identifier.project | Default project | en_US |
| rioxxterms.version | VoR | en_US |
| rioxxterms.versionofrecord | 10.1007/s40264-022-01224-w | en_US |
| rioxxterms.type | Journal Article/Review | en_US |
| refterms.dateFCD | 2024-03-13T15:05:50Z | |
| refterms.versionFCD | VoR | |
| refterms.dateFOA | 2024-03-13T15:05:50Z | |
| refterms.panel | Unspecified | en_US |
| html.description.abstract | INTRODUCTION: Drug-induced liver injury (DILI) is a rare but serious adverse event that can progress to acute liver failure (ALF). The evidence for treatment of DILI in children is scarce. OBJECTIVE: We aimed to comprehensively review the available literature on the therapies for both acetaminophen overdose (APAP) and idiosyncratic DILI in the paediatric population. METHODS: We included original articles conducted in a paediatric population ( Copyright © 2022. The Author(s). | en_US |
| rioxxterms.funder.project | 94a427429a5bcfef7dd04c33360d80cd | en_US |
