Show simple item record

dc.contributor.authorTaal, Maarten
dc.date.accessioned2016-12-20T15:56:43Z
dc.date.available2016-12-20T15:56:43Z
dc.date.issued2016-12
dc.identifier.citationClin Med (Lond). 2016 Dec;16(Suppl 6):s117-s120.language
dc.identifier.urihttp://hdl.handle.net/20.500.12904/468
dc.description.abstractChronic kidney disease (CKD) affects 8-16% of adults worldwide and is associated with multiple adverse outcomes. It includes a heterogeneous group of conditions with widely varied associated risks; risk stratification is therefore vital for clinical management. Use of the CKD Epidemiology Collaboration (CKD-EPI) equation to estimate glomerular filtration rate (GFR) instead of the Modification of Diet in Renal Disease (MDRD) equation will reduce, though not eliminate, over-diagnosis of CKD. Cystatin C is recommended as an alternative measure of GFR but is not yet widely used. A new classification system for CKD, which includes GFR and albuminuria, has been endorsed by the National Institute for Health and Care Excellence to aid risk stratification and a recently validated formula, requiring only age, gender, eGFR and albuminuria, is useful to predict risk of end-stage kidney disease (ESKD). A risk-based approach will facilitate appropriate treatment for people at high risk of developing ESKD while sparing the majority, who are at low risk, from unnecessary intervention.language
dc.language.isoenlanguage
dc.subjectChronic Kidney Diseaselanguage
dc.subjectKidney Failure Risk Equationlanguage
dc.subjectCystatin Clanguage
dc.subjectEstimated GFRlanguage
dc.subjectRisk Predictionlanguage
dc.titleChronic kidney disease: towards a risk-based approach.language
dc.typeArticlelanguage
refterms.dateFOA2021-06-03T10:08:50Z


Files in this item

Thumbnail
Name:
(552) Clin Med.pdf
Size:
86.98Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record