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    Establishing a Core Outcome Measure for Fatigue in Patients on Hemodialysis: A Standardized Outcomes in Nephrology-Hemodialysis (SONG-HD) Consensus Workshop Report.

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    Author
    Fluck, Richard
    Keyword
    Clinical Trial
    Consensus
    Core Outcome
    Dialysis Symptoms
    End Stage Renal Disease
    ESRD
    Fatigue
    Haemodialysis
    Haemodialysis
    Kidney Disease
    Life Participation
    Nephrology Research
    Outcome
    Outcome Measures
    Patient Centered Research
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    Date
    2018-03
    
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    Citation
    Am J Kidney Dis. 2018 Mar 15. pii: S0272-6386(18)30118-5. doi: 10.1053/j.ajkd.2017.12.018. [Epub ahead of print]
    Type
    Article
    URI
    http://hdl.handle.net/20.500.12904/506
    Note
    Author(s) Pre or Post Print Version Only. No PDF
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    Specialist Medicine

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      Measuring mental health outcomes in primary care: The psychometric properties of a new patient-generated outcome measure, 'PSYCHLOPS' ('psychological outcome profiles')

      Evans, Chris (2005)
      Background: Patient-generated outcome measures are rarely used in evaluating talking therapies in primary care but in other contexts they show high sensitivity to change. We have devised a novel patient-generated measure called 'PSYCHLOPS' ('Psychological Outcome Profiles'). This paper describes the psychometric properties of PSYCHLOPS. Method: Standardised responses to PSYCHLOPS, pre- and post-therapy, were compared with responses to an established measure, CORE-OM. Results: Data were obtained from 110 patients. The effect size, a measure of sensitivity to change, was -1.53 for PSYCHLOPS and -1.06 for CORE-OM (t = 5.10, P < 0.001). Pre-therapy alpha scores were 0.79 and 0.94, respectively. Change scores of both instruments correlated strongly (Spearman's rho = 0.61; P < 0.001). Detailed validity testing is reported. Conclusion: PSYCHLOPS is a sensitive measure of change after therapy. Alpha scores suggest satisfactory internal reliability. Evidence of convergent, concurrent and construct validity has been obtained. Further work is required to establish test-retest reliability. © 2005 Radcliffe Publishing.
    • Thumbnail

      Measuring mental health outcomes in primary care: The psychometric properties of a new patient-generated outcome measure, 'PSYCHLOPS' ('psychological outcome profiles')

      Evans, Chris (2005)
      Background: Patient-generated outcome measures are rarely used in evaluating talking therapies in primary care but in other contexts they show high sensitivity to change. We have devised a novel patient-generated measure called 'PSYCHLOPS' ('Psychological Outcome Profiles'). This paper describes the psychometric properties of PSYCHLOPS. Method: Standardised responses to PSYCHLOPS, pre- and post-therapy, were compared with responses to an established measure, CORE-OM. Results: Data were obtained from 110 patients. The effect size, a measure of sensitivity to change, was -1.53 for PSYCHLOPS and -1.06 for CORE-OM (t = 5.10, P < 0.001). Pre-therapy alpha scores were 0.79 and 0.94, respectively. Change scores of both instruments correlated strongly (Spearman's rho = 0.61; P < 0.001). Detailed validity testing is reported. Conclusion: PSYCHLOPS is a sensitive measure of change after therapy. Alpha scores suggest satisfactory internal reliability. Evidence of convergent, concurrent and construct validity has been obtained. Further work is required to establish test-retest reliability. © 2005 Radcliffe Publishing.
    • Thumbnail

      Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus.

      Dunkley, Colin (2019-05)
      Objective: Establishing a core set of outcomes to be evaluated and reported in intervention trials aims to improve the usefulness of health research. There is no established core outcome set (COS) for childhood epilepsies. The aim of this study was to select a COS to be used in evaluative research of interventions for children with rolandic epilepsy (RE). Methods: We followed guidance from the COMET (Core Outcome Measures in Effectiveness Trials) Initiative. First, we identified outcomes that had been measured in research through a systematic review. Second, young people with RE, parents, and professionals were invited to take part in a Delphi survey in which participants rated the importance of candidate outcomes. Last, a face‐to‐face meeting was convened to seek consensus on which outcomes were critical to include and to ratify the final COS. Results: From 37 eligible papers in the review, we identified and included 48 candidate outcomes in the survey. We sent invitations to 165 people registered to take part in the survey; of these, 102 (62%) completed Round 1, and 80 (78%) completed Round 2 (three young people, 16 parents, 61 professionals). In Round 2 we included four additional outcomes suggested by participants in Round 1. The consensus meeting included two young people, four parents, and nine professionals who were eligible to vote and ratified the COS as 39 outcomes across 10 domains. Significance: Our methodology was a proportionate and pragmatic approach toward producing a COS for evaluating research on interventions aiming to improve the health of children with RE.
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