Recent Submissions

  • COMPARISON OF OPEN CHOLECYSTECTOMY AND LAPAROSCOPIC CHOLECYSTECTOMY IN THE TREATMENT OF ACUTE CHOLECYSTITIS: A SYSTEMATIC REVIEW

    Toru, Hamza Khan (Journal of Population Therapeutics & Clinical Pharmacology, 2024-04)
    Background: Acute cholecystitis is considered the most common complication of cholelithiasis. Annually, around 64,000 people require surgical intervention for this frequent surgical disease. The normal medical practice for individuals with acute cholecystitis is to do an early laparoscopic cholecystectomy (LC). The objective of this research is to present compelling data regarding the impact of laparoscopic cholecystectomy on reducing hospitalization duration, postoperative complications, morbidity, and mortality rate, as well as to assess its overall practicality. This objective was accomplished through carrying out a methodical examination of the existing evidence in the study undertaken in this particular area. Objective: To compare the current evidences of open cholecystectomy Laparoscopic Cholecystectomy (LC) in the management of acute cholecystitis. Methods: Systematic review was carried out in accordance with the PRISMA standards. Relevant searches were conducted using PubMed, EMBASE, and CINAHL. Eligible quasi-experimental & randomized controlled experiments were conducted utilizing various Mesh terms associated with laparoscopic cholecystectomy as well as open cholecystectomy interventions. Four main outcome parameters (hospital stay, post op complications, morbidity and mortality rate) were assess on short, medium, and long-term effect. Result: The initial search yielded a total of 65 items. Following the screening process, a total of 10 publications were collected for the study. Multiple studies have consistently shown that laparoscopic cholecystectomy, when compared to open cholecystectomy, results in shorter hospital stays, reduced morbidity, and decreased postoperative problems. The outcome implies that. Laparoscopic cholecystectomy is a safe procedure for treating acute cholecystitis, with lower mortality rates, shorter hospital stays, and less postoperative problems compared to open cholecystectomy. Conclusion: The evidence of moderate quality indicates that laparoscopic cholecystectomy provides a safe and effective alternative to open cholecystectomy for patients with acute cholecystitis. It has been shown to reduce hospital stay, morbidity, mortality, and post-operative problems.