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dc.contributor.authorSelby, Nicholas
dc.contributor.authorMcIntyre, Christopher
dc.date.accessioned2016-10-13T15:51:07Z
dc.date.available2016-10-13T15:51:07Z
dc.date.issued2012-10
dc.identifier.citationBlood Purif. 2012;34(2):171-6. doi: 10.1159/000342063. Epub 2012 Oct 24.language
dc.identifier.urihttp://hdl.handle.net/20.500.12904/586
dc.descriptionAuthor(s) Pre or Post Print Version Onlylanguage
dc.description.abstractRenal replacement therapy (RRT) remains associated with a significant risk of serious complications, and critically ill patients requiring RRT continue to manifest particularly poor overall survival rates. These poor outcomes persist despite improvements in the modalities employed as well as an enhanced understanding of the effects of the extracorporeal circuit, anticoagulation, treatment doses, fluid replacement and dialysis membrane. More recently, there has been an emerging appreciation that intermittent RRT (in the chronic maintenance haemodialysis setting) is capable of generating sufficient circulatory stress to propagate additional widespread end-organ injury. The mitigation of this plethora of risks by the correct identification of complications, targeting of therapy refinements and prediction, whilst problems still remain occult, is desirable and becoming increasingly possible in the pursuit of improved outcomes in this high-mortality therapeutic field.language
dc.language.isoenlanguage
dc.subjectAcute Kidney Injurylanguage
dc.subjectChronic Kidney Injurylanguage
dc.subjectHaemodialysislanguage
dc.subjectRenal Replacement Therapylanguage
dc.subjectRRTlanguage
dc.titlePredicting and managing complications of renal replacement therapy in the critically ill.language
dc.typeArticlelanguage


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