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dc.contributor.authorHolmes, Nikki
dc.date.accessioned2020-05-06T15:15:52Z
dc.date.available2020-05-06T15:15:52Z
dc.date.issued2020
dc.identifier.citationHenry, R., Massey, R., Morgan, K., Deeks, J., Macfarlane, H., Holmes, N. & Silva, E. (2020). Evaluation of the effectiveness and acceptability of intramuscular clozapine injection: Illustrative case series. BJPsych Bulletin, 44(6), pp. 239-243.en
dc.identifier.other10.1192/bjb.2020.6
dc.identifier.urihttp://hdl.handle.net/20.500.12904/6213
dc.description.abstractAIMS AND METHOD: A series of eleven patients prescribed intramuscular clozapine at five UK sites is presented. Using routinely collected clinical data, we describe the use, efficacy and safety of this treatment modality. RESULTS: We administered 188 doses of intramuscular clozapine to eight patients. The remaining three patients accepted oral medication. With the exception of minor injection site pain and nodules, side-effects were as expected with oral clozapine, and there were no serious untoward events. Nine patients were successfully established on oral clozapine with significant improvement in their clinical presentations. CLINICAL IMPLICATIONS: Although a novel formulation in the UK, we have shown that intramuscular clozapine can be used safely and effectively when the oral route is initially refused.en
dc.description.urihttps://www.cambridge.org/core/journals/bjpsych-bulletin/article/evaluation-of-the-effectiveness-and-acceptability-of-intramuscular-clozapine-injection-illustrative-case-series/B122742C320E5AF3625097D572A0FB45en
dc.subjectAntipsychotic agentsen
dc.subjectPatient-centred careen
dc.subjectDrug administration routesen
dc.subjectInjectionsen
dc.titleEvaluation of the effectiveness and acceptability of intramuscular clozapine injection: illustrative case seriesen
dc.typeArticleen


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