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dc.contributor.authorGroom, Madeleine J.
dc.date.accessioned2017-08-24T14:53:38Z
dc.date.available2017-08-24T14:53:38Z
dc.date.issued2015
dc.identifier.citationGroom, M. J. & Cragg, L. (2015). Differential modulation of the N2 and P3 event-related potentials by response conflict and inhibition. Brain and Cognition, 97, pp.1-9.
dc.identifier.other10.1016/j.bandc.2015.04.004
dc.identifier.urihttp://hdl.handle.net/20.500.12904/7682
dc.descriptionArticle as accepted for publication in Brain and Cognition published by Elsevier available at http://dx.doi.org/10.1016/j.bandc.2015.04.004
dc.description© 2015. This manuscript is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.description.abstractBACKGROUND: Developing reliable and specific neural markers of cognitive processes is essential to improve understanding of healthy and atypical brain function. Despite extensive research there remains uncertainty as to whether two electrophysiological markers of cognitive control, the N2 and P3, are better conceptualised as markers of response inhibition or response conflict. The present study aimed to directly compare the effects of response inhibition and response conflict on the N2 and P3 event-related potentials, within-subjects.
dc.description.abstractMETHOD: A novel hybrid go/no-go flanker task was performed by 19 healthy adults aged 18-25 years while EEG data were collected. The response congruence of a central target stimulus and 4 flanking stimuli was manipulated between trials to vary the degree of response conflict. Response inhibition was required on a proportion of trials. N2 amplitude was measured at two frontal electrode sites; P3 amplitude was measured at 4 midline electrode sites.
dc.description.abstractRESULTS: N2 amplitude was greater on incongruent than congruent trials but was not enhanced by response inhibition when the stimulus array was congruent. P3 amplitude was greater on trials requiring response inhibition; this effect was more pronounced at frontal electrodes. P3 amplitude was also enhanced on incongruent compared with congruent trials.
dc.description.abstractDISCUSSION: The findings support a role for N2 amplitude as a marker of response conflict and for the frontal shift of the P3 as a marker of response inhibition. This paradigm could be applied to clinical groups to help clarify the precise nature of impaired action control in disorders such as attention deficit/hyperactivity disorders (ADHD).Copyright © 2015 Elsevier Inc. All rights reserved.
dc.description.urihttp://www.sciencedirect.com/science/article/pii/S027826261500038X
dc.formatFull text uploaded
dc.subjectAttention deficit disorder with hyperactivity
dc.subjectCognition
dc.titleDifferential modulation of the N2 and P3 event-related potentials by response conflict and inhibition
dc.typeArticle
refterms.dateFOA2021-06-11T15:50:38Z
html.description.abstractBACKGROUND: Developing reliable and specific neural markers of cognitive processes is essential to improve understanding of healthy and atypical brain function. Despite extensive research there remains uncertainty as to whether two electrophysiological markers of cognitive control, the N2 and P3, are better conceptualised as markers of response inhibition or response conflict. The present study aimed to directly compare the effects of response inhibition and response conflict on the N2 and P3 event-related potentials, within-subjects.
html.description.abstractMETHOD: A novel hybrid go/no-go flanker task was performed by 19 healthy adults aged 18-25 years while EEG data were collected. The response congruence of a central target stimulus and 4 flanking stimuli was manipulated between trials to vary the degree of response conflict. Response inhibition was required on a proportion of trials. N2 amplitude was measured at two frontal electrode sites; P3 amplitude was measured at 4 midline electrode sites.
html.description.abstractRESULTS: N2 amplitude was greater on incongruent than congruent trials but was not enhanced by response inhibition when the stimulus array was congruent. P3 amplitude was greater on trials requiring response inhibition; this effect was more pronounced at frontal electrodes. P3 amplitude was also enhanced on incongruent compared with congruent trials.
html.description.abstractDISCUSSION: The findings support a role for N2 amplitude as a marker of response conflict and for the frontal shift of the P3 as a marker of response inhibition. This paradigm could be applied to clinical groups to help clarify the precise nature of impaired action control in disorders such as attention deficit/hyperactivity disorders (ADHD).Copyright © 2015 Elsevier Inc. All rights reserved.


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