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dc.contributor.authorOrrell, Martin
dc.date.accessioned2017-09-06T12:43:51Z
dc.date.available2017-09-06T12:43:51Z
dc.date.issued2017
dc.identifier.citationRajkumar, A. P., Ballard, C., Fossey, J., Orrell, M., Moniz-Cook, E., Woods, R. T., Murray, J., Whitaker, R., Stafford, J., Knapp, M., et al. (2017). Epidemiology of pain in people with dementia living in care homes: Longitudinal course, prevalence, and treatment implications. Journal of the American Medical Directors Association, 18(5), pp.453.e1-453.e6.
dc.identifier.other10.1016/j.jamda.2017.01.024
dc.identifier.urihttp://hdl.handle.net/20.500.12904/7885
dc.description.abstractINTRODUCTION: Knowledge regarding the longitudinal course, impact, or treatment implications of pain in people with dementia living in care homes is very limited. METHODS: We investigated the people with dementia living in 67 care homes in London and Buckinghamshire, United Kingdom. Pain, dementia severity, neuropsychiatric symptoms, depression, agitation, and quality-of-life were measured using appropriate instruments at baseline (N = 967) and after 9 months (n = 629). RESULTS: Baseline prevalence of pain was 35.3% (95% CI 32.3-38.3). Pain severity was significantly correlated with dementia severity, neuropsychiatric symptoms, depression, agitation, and quality of life at both time points. Regular treatment with analgesics significantly reduced pain severity. Pain was significantly associated with more antipsychotic prescriptions. Pain was significantly associated (OR 1.48; 95% CI 1.18-1.85) with all-cause mortality during follow-up. CONCLUSIONS: Pain is an important determinant of neuropsychiatric symptoms, mortality, quality-of-life, and antipsychotic prescriptions. Improved identification, monitoring, and treatment of pain are urgent priorities to improve the health and quality-of-life for people with dementia.
dc.description.urihttp://www.jamda.com/article/S1525-8610(17)30071-3/abstract
dc.subjectPain
dc.subjectDementia
dc.titleEpidemiology of pain in people with dementia living in care homes: Longitudinal course, prevalence, and treatment implications
dc.typeArticle
html.description.abstractINTRODUCTION: Knowledge regarding the longitudinal course, impact, or treatment implications of pain in people with dementia living in care homes is very limited. METHODS: We investigated the people with dementia living in 67 care homes in London and Buckinghamshire, United Kingdom. Pain, dementia severity, neuropsychiatric symptoms, depression, agitation, and quality-of-life were measured using appropriate instruments at baseline (N = 967) and after 9 months (n = 629). RESULTS: Baseline prevalence of pain was 35.3% (95% CI 32.3-38.3). Pain severity was significantly correlated with dementia severity, neuropsychiatric symptoms, depression, agitation, and quality of life at both time points. Regular treatment with analgesics significantly reduced pain severity. Pain was significantly associated with more antipsychotic prescriptions. Pain was significantly associated (OR 1.48; 95% CI 1.18-1.85) with all-cause mortality during follow-up. CONCLUSIONS: Pain is an important determinant of neuropsychiatric symptoms, mortality, quality-of-life, and antipsychotic prescriptions. Improved identification, monitoring, and treatment of pain are urgent priorities to improve the health and quality-of-life for people with dementia.


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