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dc.contributor.authorDonaldson, James
dc.date.accessioned2017-11-28T11:47:22Z
dc.date.available2017-11-28T11:47:22Z
dc.date.issued2017-12
dc.identifier.citationThorax. 2017 Dec;72(12):1154-1163. doi: 10.1136/thoraxjnl-2017-210764.en
dc.identifier.urihttp://hdl.handle.net/20.500.12904/805
dc.descriptionAuthor(s) Pre or Post Print Version Onlyen
dc.description.abstractPulmonary arteriovenous malformations (PAVMs) are structurally abnormal vascular communications that provide a continuous right-to-left shunt between pulmonary arteries and veins. Their importance stems from the risks they pose (>1 in 4 patients will have a paradoxical embolic stroke, abscess or myocardial infarction while life-threatening haemorrhage affects 1 in 100 women in pregnancy), opportunities for risk prevention, surprisingly high prevalence and under-appreciation, thus representing a challenging condition for practising healthcare professionals. The driver for the current Clinical Statement was the plethora of new data since previous hereditary haemorrhagic telangiectasia (HHT) guidelines generated in 2006 and a systematic Cochrane Review for PAVM embolisation in 2011. The British Thoracic Society (BTS) identified key areas in which there is now evidence to drive a change in practice. Due to the paucity of data in children, this Statement focused on adults over 16 years. The Statement spans the management of PAVMs already known to be present (interventional and medical), screening and diagnosis (for PAVMs and HHT) and follow-up of patients following a first diagnosis, intervention or negative screen for PAVMs. The Good Practice Points (in bold) were generated for a target audience of general respiratory, medical and specialist clinicians and were approved by the BTS Standards of Care Committee, before formal peer review and public consultation. The Statement spans embolisation treatment, accessory medical management and issues related to the likelihood of underlying HHT.en
dc.language.isoenen
dc.subjectPulmonary Arteriovenous Malformationsen
dc.titleBritish Thoracic Society Clinical Statement on Pulmonary Arteriovenous Malformations.en
dc.typeArticleen


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