Recurrent hyponatremia associated with sertraline and lofepramine
dc.contributor.author | Bouman, Walter P. | |
dc.contributor.author | Johnson, Hazel | |
dc.date.accessioned | 2017-10-20T14:02:10Z | |
dc.date.available | 2017-10-20T14:02:10Z | |
dc.date.issued | 1997 | |
dc.identifier.citation | Bouman, W. P., Johnson, H., Trescoli-Serrano, C. & Jones, R. G. (1997). Recurrent hyponatremia associated with sertraline and lofepramine. The American Journal of Psychiatry, 154 (4), pp.580a-580. | en |
dc.identifier.other | 10.1176/ajp.154.4.580a | |
dc.identifier.uri | http://hdl.handle.net/20.500.12904/8520 | |
dc.description.abstract | Reports a case of recurrent hyponatremia in a 78-yr-old woman with depression. One week after the start of sertraline (50 mg/day) therapy, S was admitted to hospital for complaints of feeling depressed, weak, and lethargic. The setraline treatment was discontinued and fluids were restricted to 1 liter/day. After 1 wk, the hyponatremia had resolved and a regimen of lofepramine (70 mg/day) was started. Two weeks after starting the lofepramine, her serum sodium level fell, and the serum and urine osmolality rose. Lofepramine was discontinued and the 1 liter restriction was reinstated. Everything normalized within a week. Finally, the S was treated with ECT. She made a full recovery and was placed on clozapine. (PsycINFO Database Record (c) 2016 APA, all rights reserved) | |
dc.subject | Depression | en |
dc.subject | Drug therapy | en |
dc.title | Recurrent hyponatremia associated with sertraline and lofepramine | en |
dc.type | Article | |
html.description.abstract | Reports a case of recurrent hyponatremia in a 78-yr-old woman with depression. One week after the start of sertraline (50 mg/day) therapy, S was admitted to hospital for complaints of feeling depressed, weak, and lethargic. The setraline treatment was discontinued and fluids were restricted to 1 liter/day. After 1 wk, the hyponatremia had resolved and a regimen of lofepramine (70 mg/day) was started. Two weeks after starting the lofepramine, her serum sodium level fell, and the serum and urine osmolality rose. Lofepramine was discontinued and the 1 liter restriction was reinstated. Everything normalized within a week. Finally, the S was treated with ECT. She made a full recovery and was placed on clozapine. (PsycINFO Database Record (c) 2016 APA, all rights reserved) |