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dc.contributor.authorBouman, Walter P.
dc.contributor.authorJohnson, Hazel
dc.date.accessioned2017-10-20T14:02:10Z
dc.date.available2017-10-20T14:02:10Z
dc.date.issued1997
dc.identifier.citationBouman, W. P., Johnson, H., Trescoli-Serrano, C. & Jones, R. G. (1997). Recurrent hyponatremia associated with sertraline and lofepramine. The American Journal of Psychiatry, 154 (4), pp.580a-580.en
dc.identifier.other10.1176/ajp.154.4.580a
dc.identifier.urihttp://hdl.handle.net/20.500.12904/8520
dc.description.abstractReports a case of recurrent hyponatremia in a 78-yr-old woman with depression. One week after the start of sertraline (50 mg/day) therapy, S was admitted to hospital for complaints of feeling depressed, weak, and lethargic. The setraline treatment was discontinued and fluids were restricted to 1 liter/day. After 1 wk, the hyponatremia had resolved and a regimen of lofepramine (70 mg/day) was started. Two weeks after starting the lofepramine, her serum sodium level fell, and the serum and urine osmolality rose. Lofepramine was discontinued and the 1 liter restriction was reinstated. Everything normalized within a week. Finally, the S was treated with ECT. She made a full recovery and was placed on clozapine. (PsycINFO Database Record (c) 2016 APA, all rights reserved)
dc.subjectDepressionen
dc.subjectDrug therapyen
dc.titleRecurrent hyponatremia associated with sertraline and lofepramineen
dc.typeArticle
html.description.abstractReports a case of recurrent hyponatremia in a 78-yr-old woman with depression. One week after the start of sertraline (50 mg/day) therapy, S was admitted to hospital for complaints of feeling depressed, weak, and lethargic. The setraline treatment was discontinued and fluids were restricted to 1 liter/day. After 1 wk, the hyponatremia had resolved and a regimen of lofepramine (70 mg/day) was started. Two weeks after starting the lofepramine, her serum sodium level fell, and the serum and urine osmolality rose. Lofepramine was discontinued and the 1 liter restriction was reinstated. Everything normalized within a week. Finally, the S was treated with ECT. She made a full recovery and was placed on clozapine. (PsycINFO Database Record (c) 2016 APA, all rights reserved)


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