Assessing effectiveness of treatment of depression in primary care: Partially randomised preference trial
| dc.contributor.author | Duggan, Conor | |
| dc.date.accessioned | 2017-09-20T15:51:49Z | |
| dc.date.available | 2017-09-20T15:51:49Z | |
| dc.date.issued | 2000 | |
| dc.identifier.citation | Bedi, N., Chilvers, C., Churchill, R., Dewey, M., Duggan, C., Fielding, K., Gretton, V., Miller, P., Harrison, G., Lee, A., et al. (2000). Assessing effectiveness of treatment of depression in primary care: Partially randomised preference trial. The British Journal of Psychiatry, 177 (4), pp.312-318. | |
| dc.identifier.other | 10.1192/bjp.177.4.312 | |
| dc.identifier.uri | http://hdl.handle.net/20.500.12904/8564 | |
| dc.description.abstract | Background: There is a mismatch between the wish of a patient with depression to have counselling and the prescription of antidepressants by the doctor. Aims: To determine whether counselling is as effective as antidepressants for depression in primary care and whether allowing patients to choose their treatment affects their response. Method: A partially randomised preference trial, with patients randomised to either antidepressants or counselling or given their choice of either treatment. The treatment and follow-up were identical in the randomised and patient preference arms. Results: There were 103 randomised and 220 preference patients in the trial. We found: No differences in the baseline characteristics of the randomised and preference groups; that the two treatments were equally effective at 8 weeks, both for the randomised group and when the randomised and patient preference groups for a particular treatment were combined; and that expressing a preference for either treatment conferred no additional benefit on outcome. Conclusions: These data challenge several assumptions about the most appropriate treatment for depression in a primary care setting. Declaration of interest: None. The NHS Executive, Trent, funded the study. | |
| dc.description.uri | https://www.cambridge.org/core/journals/the-british-journal-of-psychiatry/article/assessing-effectiveness-of-treatment-of-depression-in-primary-care/57C445F92C7C38406E460028628251C6 | |
| dc.subject | Depression | |
| dc.title | Assessing effectiveness of treatment of depression in primary care: Partially randomised preference trial | |
| dc.type | Article | |
| html.description.abstract | Background: There is a mismatch between the wish of a patient with depression to have counselling and the prescription of antidepressants by the doctor. Aims: To determine whether counselling is as effective as antidepressants for depression in primary care and whether allowing patients to choose their treatment affects their response. Method: A partially randomised preference trial, with patients randomised to either antidepressants or counselling or given their choice of either treatment. The treatment and follow-up were identical in the randomised and patient preference arms. Results: There were 103 randomised and 220 preference patients in the trial. We found: No differences in the baseline characteristics of the randomised and preference groups; that the two treatments were equally effective at 8 weeks, both for the randomised group and when the randomised and patient preference groups for a particular treatment were combined; and that expressing a preference for either treatment conferred no additional benefit on outcome. Conclusions: These data challenge several assumptions about the most appropriate treatment for depression in a primary care setting. Declaration of interest: None. The NHS Executive, Trent, funded the study. |